Hassan EL FERTIT’s Post

Insular glioma surgery is one of the biggest neurosurgical challenge. Here, we report the Sainte-Anne GHU Paris experience in a two-part article just published in Neurosurgery. From a series of 149 adult patients surgically treated for an insular diffuse glioma, we highlight that: 1) Awake surgery preserving the brain connectivity is safe, allows larger resections for insular diffuse gliomas than asleep resection, and positively impacts overall survival. 2) With awake surgery, the median extent of resection is 94%; seizure control improves from 69% preoperatively to 89% postoperatively; 6-mo postoperative neurocognitive performance improves from 5% to 24% in the tested domains; and 74% of patients resume their employment postoperatively. 3) Functional mapping under awake conditions has to be performed intraoperatively in each patient to guide surgical approach and resection of insular diffuse gliomas in right and left hemispheres. 4) We provide a 3-dimensional atlas of resectability based on frequency atlases of opercula eloquence and of subcortical eloquent anatomic boundaries. 5) Insular diffuse gliomas should be referred and managed at centers that do awake surgery routinely => we are at your disposal. https://lnkd.in/dkQNxkt2 https://lnkd.in/dsik_Eti

RHESOU: HERAULT Premier registre spécialisé en onco-urologie de France Lancé hier depuis l’ICM-Val D’Aurelle Montpellier